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Each ml of Testosteron depo 5x1ml contains 250mg testosterone enanthate
Each ml of Testosteron depo 5x1ml contains:
- Testosterone enanthate 250mg
- Oil base q.s.
Description of Testosteron depo 5x1ml
Testosteron depo 5x1ml provides testosterone enanthate, a derivative of the primary endogenous androgen testosterone, for intramuscular administration.
Indications of Testosteron depo 5x1ml
Testosterone enanthate is indicated for replacement therapy in conditions associated with a deficiency or absence of endogenous testosterone. Primary hypogonadism: Testicular failure due to cryptorchisdism, bilateral torsion, orchitis, vanishing testis syndrome, or orchidectonly.
Idiopathic gonadotropin or luteinizing hormone-releasing hormone (LH RH) deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.
Testosterone enanthate may be used to stimulate puberty in carefully selected males with c1early delayed puberty.
Metastatic mammary cancer:
Testosterone enanthate may be used secondarily in women with advancing inoperable metastatie mammary cancer who are one to five years postmenopausal. It has also been used in premenopausal women with breast cancer who have benefited from oophorectomy and are considered to have a hormone-responsive tumor.
Cllnical pharmacology of Testosteron depo 5x1ml
Endogenous androgens are responsible for the normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and auxillary hair; laryngeal enlargement; vocal chord thickening; alterations in body musculature; and fat distribution. Androgens are responsible for the growth spurt of adolescence and for the eventual termination of linear growth, which is brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates but may cause a disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of growth process. Androgens have been reported to stimulate the production of red blood cells by enhancing the production of erythropoietic stimulating factor. During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH).
Adverse reactions of Testosteron depo 5x1ml
Endocrine and Urogenital, Female:
The most common side effects of androgen therapy are amenorrhea and other menstrual irregularities, inhibition of gonadotropin secretion, and virilization, including deepening of the voice and clitoral enlargement.
Gynecomastia, and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages.
Skin and appendages:
Hirsutism, male pattern baldness, and acne.
Fluid and Electrolyte Disturbances:
Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
Nausea, cholestatic jaundice, alterations in liver function tests; rarely, hepatocellular neoplasms, peliosis hepatitis.
Suppression of clotting factors II ,V, VII, and Xl; bleeding in patients on concomitant anticoagulant therapy.
Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
Presentation of Testosteron depo 5x1ml
Testosteron depo 5x1ml come as 250 mg/ml (1ml ampoules / 10 ml multiple dose vials).
Storage of Testosteron depo 5x1ml
Store in a cool and dry place. Protect from light. Warming and rotating the vial between the palms of the hands will redissolve any crystals that may have formed during storage at low temperatures.
Manufacturer of Testosteron depo 5x1ml
Testosteron depo 5x1ml is manufactured by Galenika